GPRC5A polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GPRC5A.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GPRC5A.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The GPRC5A polyclonal antibody (Cat # PAB4823) is used in Western blot to detect GPRC5A in A-375 cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — GPRC5A
Entrez GeneID
9052Protein Accession#
NP_003970Gene Name
GPRC5A
Gene Alias
GPCR5A, RAI3, RAIG1
Gene Description
G protein-coupled receptor, family C, group 5, member A
Omim ID
604138Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq
Other Designations
retinoic acid induced 3|retinoic acid responsive
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Interactome
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Disease
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Publication Reference
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Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C).
Robbins MJ, Michalovich D, Hill J, Calver AR, Medhurst AD, Gloger I, Sims M, Middlemiss DN, Pangalos MN.
Genomics 2000 Jul; 67(1):8.
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Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor.
Cheng Y, Lotan R.
The Journal of Biological Chemistry 1998 Dec; 273(52):35008.
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Identification by differential display of a mRNA specifically induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in T84 human colon carcinoma cells.
E G Cafferata, A M Gonzalez-Guerrico, O H Pivetta, T A Santa-Coloma.
Cellular and Molecular Biology (Noisy-le-Grand, France) 1996 Jul; 42(5):797.
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Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C).
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