OAS3 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
The OAS3 polyclonal antibody (Cat # PAB4812) is used in Western blot to detect OAS3 in A-375 cell lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of OAS3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human OAS3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The OAS3 polyclonal antibody (Cat # PAB4812) is used in Western blot to detect OAS3 in A-375 cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — OAS3
Entrez GeneID
4940Protein Accession#
Q9Y6K5Gene Name
OAS3
Gene Alias
MGC133260, p100
Gene Description
2'-5'-oligoadenylate synthetase 3, 100kDa
Omim ID
603351Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. [provided by RefSeq
Other Designations
2'-5'-oligoadenylate synthetase 3 (100 kD)|2'-5'oligoadenylate synthetase 3|2'-5'oligoadenylate synthetase p100
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Interactome
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Disease
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Publication Reference
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Molecular basis of T cell-mediated recognition of pancreatic cancer cells.
Ito M, Shichijo S, Tsuda N, Ochi M, Harashima N, Saito N, Itoh K.
Cancer Research 2001 Mar; 61(5):2038.
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Characterization of the gene encoding the 100-kDa form of human 2',5' oligoadenylate synthetase.
Rebouillat D, Hovnanian A, David G, Hovanessian AG, Williams BR.
Genomics 2000 Dec; 70(2):232.
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The 100-kDa 2',5'-oligoadenylate synthetase catalyzing preferentially the synthesis of dimeric pppA2'p5'A molecules is composed of three homologous domains.
Rebouillat D, Hovnanian A, Marie I, Hovanessian AG.
The Journal of Biological Chemistry 1999 Jan; 274(3):1557.
Application：IF, WB-Tr, Human, HeLa cells.
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Molecular basis of T cell-mediated recognition of pancreatic cancer cells.
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