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Last updated: 2016/12/4
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MMP25 polyclonal antibody

  • Catalog # : PAB4790
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MMP25.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MMP25.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1:100-500)
    Flow cytometry (1:10-50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • The MMP25 polyclonal antibody (Cat # PAB4790) is used in Western blot to detect MMP25 in mouse liver tissue lysate (lane 1) and HL-60 cell lysate (lane 2) lysate.
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Gene Name:
  • MMP25
  • Gene Alias:
  • MMP20,MMP20A,MMPL1,MT-MMP6,MT6-MMP
  • Gene Description:
  • matrix metallopeptidase 25
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq
  • Other Designations:
  • leukolysin,matrix metallopeptidase-like 1,matrix metalloproteinase 20,matrix metalloproteinase 25,matrix metalloproteinase-like 1,membrane-type 6 matrix metalloproteinase
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