MMP11 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
The MMP11 polyclonal antibody (Cat # PAB4780) is used in Western blot to detect MMP11 in mouse liver lysate.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MMP11.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MMP11.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
The MMP11 polyclonal antibody (Cat # PAB4780) is used in Western blot to detect MMP11 in mouse liver lysate.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — MMP11
Entrez GeneID
4320Protein Accession#
MM11_HUMANGene Name
MMP11
Gene Alias
SL-3, ST3, STMY3
Gene Description
matrix metallopeptidase 11 (stromelysin 3)
Omim ID
185261Gene Ontology
HyperlinkGene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq
Other Designations
matrix metalloproteinase 11|matrix metalloproteinase 11 (stromelysin 3)|stromelysin 3|stromelysin III
-
Disease
-
Publication Reference
-
PINCH-2 presents functional copy number variation and suppresses migration of colon cancer cells by paracrine activity.
Park CH, Rha SY, Ahn JB, Shin SJ, Kwon WS, Kim TS, An S, Kim NK, Yang WI, Chung HC.
International Journal of Cancer 2015 May; 136(10):2273.
Application：WB, Human, HCT-116 cells.
-
Structure and promoter characterization of the human stromelysin-3 gene.
Anglard P, Melot T, Guerin E, Thomas G, Basset P.
The Journal of Biological Chemistry 1995 Sep; 270(35):20337.
Application：WB-Ce, WB-Tr, Human, Mammalian cells.
-
A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas.
Basset P, Bellocq JP, Wolf C, Stoll I, Hutin P, Limacher JM, Podhajcer OL, Chenard MP, Rio MC, Chambon P.
Nature 1990 Dec; 348(6303):699.
-
PINCH-2 presents functional copy number variation and suppresses migration of colon cancer cells by paracrine activity.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com