MAGEA6 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
The MAGEA6 polyclonal antibody (Cat # PAB4748) is used in Western blot to detect MAGEA6 in A-549 cell lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MAGEA6.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MAGEA6.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The MAGEA6 polyclonal antibody (Cat # PAB4748) is used in Western blot to detect MAGEA6 in A-549 cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MAGEA6
Entrez GeneID
4105Protein Accession#
NP_005354Gene Name
MAGEA6
Gene Alias
MAGE-3b, MAGE3B, MAGE6, MGC52297
Gene Description
melanoma antigen family A, 6
Omim ID
300176Gene Ontology
HyperlinkGene Summary
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
MAGE-6 antigen|OTTHUMP00000024223|melanoma-associated antigen 6
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Interactome
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Publication Reference
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MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma.
Tatsumi T, Kierstead LS, Ranieri E, Gesualdo L, Schena FP, Finke JH, Bukowski RM, Brusic V, Sidney J, Sette A, Logan TF, Kasamon YL, Slingluff CL Jr, Kirkwood JM, Storkus WJ.
Clinical Cancer Research 2003 Mar; 9(3):947.
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Sequence analysis of the MAGE gene family encoding human tumor-rejection antigens.
Imai Y, Shichijo S, Yamada A, Katayama T, Yano H, Itoh K.
Gene 1995 Jul; 160(2):287.
Application：WB-Ce, WB-Tr, Human, Cancer cells, Mammalian cells.
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MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma.
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