The CDX2 polyclonal antibody (Cat # PAB4714) is used in Western blot to detect CDX2 in placenta tissue lysate.
Western Blot (Transfected lysate)
Western blot analysis of CDX2 (arrow) using rabbit CDX2 polyclonal antibody (Cat # PAB4714) . 293 cell lysate (2 &miceo;g/lane) either nontransfected (Lane 1) or transiently transfected with the CDX2 gene (Lane 2) (Origene Technologies) .
Formalin-fixed and paraffin-embedded human cancer tissue reacted with CDX2 polyclonal antibody (Cat # PAB4714) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
OTTHUMP00000018176,caudal type homeo box transcription factor 2,caudal type homeobox transcription factor 2