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Last updated: 2016/12/4
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ABCB4 polyclonal antibody

  • Catalog # : PAB4698
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ABCB4.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to amino acids 624-654 of human ABCB4.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of ABCB4 polyclonal antibody (Cat # PAB4698) in Mouse heart tissue lysate ABCB4 (Arrow) was detected using purified polyclonal antibody.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with ABCB4 polyclonal antibody (Cat # PAB4698) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5244
  • Protein Accession#:
  • NP_061337;P21439
  • Gene Name:
  • ABCB4
  • Gene Alias:
  • ABC21,GBD1,MDR2,MDR2/3,MDR3,PFIC-3,PGY3
  • Gene Description:
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • Gene Summary:
  • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette, subfamily B, member 4,OTTHUMP00000025014,P glycoprotein 3/multiple drug resistance 3,P-glycoprotein-3/multiple drug resistance-3,multidrug resistance protein 3,multiple drug resistance 3
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