DGUOK polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of DGUOK polyclonal antibody (Cat # PAB4644) in mouse kidney tissue lysate (35 ug/lane). DGUOK (arrow) was detected using the purified DGUOK polyclonal antibody (Cat # PAB4644) (1 : 60 dilution).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DGUOK.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human DGUOK.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of DGUOK polyclonal antibody (Cat # PAB4644) in mouse kidney tissue lysate (35 ug/lane). DGUOK (arrow) was detected using the purified DGUOK polyclonal antibody (Cat # PAB4644) (1 : 60 dilution).Enzyme-linked Immunoabsorbent Assay
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Gene Info — DGUOK
Entrez GeneID
1716Protein Accession#
NP_550438Gene Name
DGUOK
Gene Alias
dGK
Gene Description
deoxyguanosine kinase
Gene Ontology
HyperlinkGene Summary
In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000160251|OTTHUMP00000160252|deoxyguanosine kinase, mitochondrial
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Interactome
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Pathway
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Disease
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