PICK1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PICK1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PICK1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The PICK1 polyclonal antibody (Cat # PAB4631) is used in Western blot to detect PICK1 in Y-79 cell lysate .Enzyme-linked Immunoabsorbent Assay
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Gene Info — PICK1
Entrez GeneID
9463Protein Accession#
Q9NRD5Gene Name
PICK1
Gene Alias
MGC15204, PICK, PRKCABP
Gene Description
protein interacting with PRKCA 1
Omim ID
605926Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000028509|PRKCA-binding protein|protein interacting with C kinase 1|protein kinase C, alpha binding protein
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Interactome
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Disease
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