CSNK2B polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CSNK2B.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CSNK2B.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of CSNK2B (arrow) using rabbit CSNK2B polyclonal antibody (Cat # PAB4624). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CSNK2B gene (Lane 2) (Origene Technologies).Enzyme-linked Immunoabsorbent Assay
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Gene Info — CSNK2B
Entrez GeneID
1460Protein Accession#
NP_001311;P67870Gene Name
CSNK2B
Gene Alias
CK2B, CK2N, CSK2B, G5A, MGC138222, MGC138224
Gene Description
casein kinase 2, beta polypeptide
Omim ID
115441Gene Ontology
HyperlinkGene Summary
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq
Other Designations
Casein kinase II beta subunit|OTTHUMP00000029060|OTTHUMP00000029063|OTTHUMP00000029064|alternative name: G5a, phosvitin|phosvitin
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Publication Reference
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CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolism.
Schwartz EI, Intine RV, Maraia RJ.
Molecular and Cellular Biology 2004 Nov; 24(21):9580.
Application:WB-Tr, Human, HEK 293 cells.
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Direct regulation of microtubule dynamics by protein kinase CK2.
Lim AC, Tiu SY, Li Q, Qi RZ.
The Journal of Biological Chemistry 2004 Feb; 279(6):4433.
Application:IF, WB-Tr, Monkey, COS-7 cells.
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Casein kinase II-mediated phosphorylation regulates alpha-synuclein/synphilin-1 interaction and inclusion body formation.
Lee G, Tanaka M, Park K, Lee SS, Kim YM, Junn E, Lee SH, Mouradian MM.
The Journal of Biological Chemistry 2003 Nov; 279(8):6834.
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CK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolism.
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