CKMT2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CKMT2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CKMT2.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
The CKMT2 polyclonal antibody (Cat # PAB4617) is used in Western blot to detect CKMT2 in mouse muscle tissue lysate .Enzyme-linked Immunoabsorbent Assay
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Gene Info — CKMT2
Entrez GeneID
1160Protein Accession#
P17540Gene Name
CKMT2
Gene Alias
SMTCK
Gene Description
creatine kinase, mitochondrial 2 (sarcomeric)
Omim ID
123295Gene Ontology
HyperlinkGene Summary
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000147542|basic-type mitochondrial creatine kinase|sarcomeric mitochondrial creatine kinase
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