PDK3 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PDK3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PDK3.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Transfected lysate)
Western blot analysis of PDK3 (arrow) using rabbit PDK3 polyclonal antibody (Cat # PAB4563). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDK3 gene (Lane 2) (Origene Technologies).Enzyme-linked Immunoabsorbent Assay
-
Gene Info — PDK3
Entrez GeneID
5165Protein Accession#
NP_005382;Q15120Gene Name
PDK3
Gene Alias
-
Gene Description
pyruvate dehydrogenase kinase, isozyme 3
Omim ID
602526Gene Ontology
HyperlinkGene Summary
O
Other Designations
OTTHUMP00000023083|pyruvate dehydrogenase kinase, isoenzyme 3
-
Interactome
-
Publication Reference
-
Satellite glia as a critical component of diabetic neuropathy: Role of lipocalin-2 and pyruvate dehydrogenase kinase-2 axis in the dorsal root ganglion.
Anup Bhusal, Md Habibur Rahman, Won-Ha Lee, In-Kyu Lee, Kyoungho Suk.
Glia 2021 Apr; 69(4):971.
Application:WB-Ti, Mouse, Mouse dorsal root ganglion.
-
Astrocytic pyruvate dehydrogenase kinase-2 is involved in hypothalamic inflammation in mouse models of diabetes.
Md Habibur Rahman, Anup Bhusal, Jae-Hong Kim, Mithilesh Kumar Jha, Gyun Jee Song, Younghoon Go, Il-Sung Jang, In-Kyu Lee, Kyoungho Suk.
Nature Communications 2020 Nov; 11(1):5906.
Application:WB-Ti, Mouse , Mouse brain, Mouse hypothalamus.
-
Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells.
McFate T, Mohyeldin A, Lu H, Thakar J, Henriques J, Halim ND, Wu H, Schell MJ, Tsang TM, Teahan O, Zhou S, Califano JA, Jeoung NH, Harris RA, Verma A.
The Journal of Biological Chemistry 2008 Jun; 283(33):22700.
-
Satellite glia as a critical component of diabetic neuropathy: Role of lipocalin-2 and pyruvate dehydrogenase kinase-2 axis in the dorsal root ganglion.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com