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Last updated: 2016/10/23
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LATS2 polyclonal antibody

  • Catalog # : PAB4559
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of LATS2.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to amino acids 195-224 at internal region of human LATS2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1:100-500)
    Immunohistochemistry (1:10-50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • The LATS2 polyclonal antibody (Cat # PAB4559) is used in Western blot to detect LATS2 in NIH/3T3 cell lysate .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with LATS2 polyclonal antibody (Cat # PAB4559) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Protein Accession#:
  • NP_055387;Q9P2X1
  • Gene Name:
  • LATS2
  • Gene Alias:
  • FLJ13161,KPM
  • Gene Description:
  • LATS, large tumor suppressor, homolog 2 (Drosophila)
  • Gene Summary:
  • This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq
  • Other Designations:
  • LATS (large tumor suppressor, Drosophila) homolog 2,LATS, large tumor suppressor, homolog 2,OTTHUMP00000018106,kinase phosphorylated during mitosis protein,serine/threonine kinase KPM,warts-like kinase
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