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Last updated: 2017/5/21
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GRK6 polyclonal antibody

  • Catalog # : PAB4520
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of GRK6.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GRK6.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1:100-500)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
    Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA,Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of GRK6 polyclonal antibody (Cat # PAB4520) in mouse heart tissue lysate . GRK6 (arrow) was detected using purified GRK6 polyclonal antibody (Cat # PAB4520) . Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence .
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of GRK6 polyclonal antibody (Cat # PAB4520) in HeLa cell lysate . GRK6 (arrow) was detected using purified GRK6 polyclonal antibody (Cat # PAB4520) . Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human cancer tissue reacted with GRK6 polyclonal antibody (Cat # PAB4520) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . BC = breast carcinoma .
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2870
  • Gene Name:
  • GRK6
  • Gene Alias:
  • FLJ32135,GPRK6
  • Gene Description:
  • G protein-coupled receptor kinase 6
  • Gene Summary:
  • This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
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