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Last updated: 2018/1/14
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AURKC polyclonal antibody

  • Catalog # : PAB4510
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of AURKC.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human AURKC.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1:100-500)
    Immunofluorescence (1:100-500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • The AURKC polyclonal antibody (Cat # PAB4510) is used in Western blot to detect AURKC in lysates of 293 cells expressing Flag tag (lane 1) , Flag-tagged AURKA (lane 2) , Flag-tagged AURKB (lane 3) , Flag-tagged AURKC (lane 4) .
  • Immunofluorescence
  • Immunofluorescence
  • In the immunofluorescence experiment, staining of HeLa cells expressing GFP-AURKC is performed at different cellular mitotic stages with The AURKC polyclonal antibody (Cat # PAB4510) (column A), GFP fluorescence (column B), DAPI nuclear staining (column C), and antiAURKC merged to DAPI staining (column D). Data is kindly provided by Drs . K . Sasai and S . Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6795
  • Gene Name:
  • Gene Alias:
  • AIE2,AIK3,AurC,STK13,aurora-C
  • Gene Description:
  • aurora kinase C
  • Gene Summary:
  • This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • aurora/IPL1-related kinase 3,aurora/IPL1/EG2 protein 2,serine/threonine kinase 13 (aurora/IPL1-like)
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