GPC6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GPC6.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 24-46 at N-terminus of human GPC6.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Saturated ammonium sulfate (SAS) precipitation
Recommend Usage
ELISA
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide).
Storage Instruction
Store at 4°C for up to 2 weeks. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of GPC6 polyclonal antibody (Cat # PAB4470) in K-562 cell line lysates (35 ug/lane). GPC6 (arrow) was detected using the purified GPC6 polyclonal antibody (Cat # PAB4470) (1 : 60 dilution).Enzyme-linked Immunoabsorbent Assay
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Gene Info — GPC6
Entrez GeneID
10082Protein Accession#
NP_005699; Q9Y625Gene Name
GPC6
Gene Alias
MGC126288
Gene Description
glypican 6
Omim ID
604404Gene Ontology
HyperlinkGene Summary
The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. [provided by RefSeq
Other Designations
OTTHUMP00000018552|bA158B14.1 (glypican 6)|bA62D23.1 (glypican 6)|bA632L2.2 (glypican 6)|glypican proteoglycan 6
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Interactome
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Disease
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Publication Reference
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Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans.
Veugelers M, De Cat B, Ceulemans H, Bruystens AM, Coomans C, Durr J, Vermeesch J, Marynen P, David G.
The Journal of Biological Chemistry 1999 Sep; 274(38):26968.
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GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC4 and is colocalized with GPC5 on human chromosome 13.
Paine-Saunders S, Viviano BL, Saunders S.
Genomics 1999 May; 57(3):455.
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Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans.
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