MYO1C polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MYO1C.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MYO1C.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of MYO1C polyclonal antibody (Cat # PAB4467) in K-562 cell line lysates (35 ug/lane). MYO1C (arrow) was detected using the purified MYO1C polyclonal antibody (Cat # PAB4467) (1 : 60 dilution).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with MYO1C polyclonal antibody (Cat # PAB4467) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . -
Gene Info — MYO1C
Entrez GeneID
4641Protein Accession#
NP_001074248;O00159Gene Name
MYO1C
Gene Alias
FLJ23903, MMI-beta, MMIb, NMI, myr2
Gene Description
myosin IC
Omim ID
606538Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq
Other Designations
myosin-I beta|nuclear myosin I
-
Interactome
-
Disease
-
Publication Reference
-
Cloning of the genes encoding two murine and human cochlear unconventional type I myosins.
Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C.
Genomics 1997 Mar; 40(2):332.
-
Cloning of the genes encoding two murine and human cochlear unconventional type I myosins.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com