DSCR3 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of Y-79 cell lysate (35 ug/lane) with DSCR3 polyclonal antibody (Cat # PAB4392).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DSCR3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human DSCR3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Y-79 cell lysate (35 ug/lane) with DSCR3 polyclonal antibody (Cat # PAB4392).Enzyme-linked Immunoabsorbent Assay
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Gene Info — DSCR3
Entrez GeneID
10311Protein Accession#
NP_006043;O14972Gene Name
DSCR3
Gene Alias
DCRA, DSCRA, MGC117385
Gene Description
Down syndrome critical region gene 3
Omim ID
605298Gene Ontology
HyperlinkGene Summary
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq
Other Designations
Down syndrome critical region protein 3|Down syndrome critical region protein A
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Interactome
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Publication Reference
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Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.
Dahmane N, Ghezala GA, Gosset P, Chamoun Z, Dufresne-Zacharia MC, Lopes C, Rabatel N, Gassanova-Maugenre S, Chettouh Z, Abramowski V, Fayet E, Yaspo ML, Korn B, Blouin JL, Lehrach H, Poutska A, Antonarakis SE, Sinet PM, Creau N, Delabar JM.
Genomics 1998 Feb; 48(1):12.
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A novel gene isolated from human placenta located in Down syndrome critical region on chromosome 21.
Nakamura A, Hattori M, Sakaki Y.
DNA Research 1997 Oct; 4(5):321.
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Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.
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