Western blot analysis of TRIM69 polyclonal antibody (Cat # PAB4371) in K-562 cell line lysates (35 ug/lane). TRIM69 (arrow) was detected using the purified TRIM69 polyclonal antibody (Cat # PAB4371) (1 : 60 dilution).
This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
ring finger protein 36,trimless,tripartite motif protein 69