Western blot analysis of YY1 polyclonal antibody (Cat # PAB4360) in HeLa cell lysate . YY1 (arrow) was detected using purified YY1 polyclonal antibody (Cat # PAB4360) . Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence .
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with YY1 polyclonal antibody (Cat # PAB4360) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq