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ZMPSTE24 polyclonal antibody

  • Catalog # : PAB4318
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ZMPSTE24.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human ZMPSTE24.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1:100-500)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • The ZMPSTE24 polyclonal antibody (Cat # PAB4318) is used in Western blot to detect ZMPSTE24 in T-47D cell lysate .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with ZMPSTE24 polyclonal antibody (Cat # PAB4318) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • ZMPSTE24
  • Gene Alias:
  • FACE-1,FACE1,FLJ14968,STE24,Ste24p
  • Gene Description:
  • zinc metallopeptidase (STE24 homolog, S. cerevisiae)
  • Gene Summary:
  • This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq
  • Other Designations:
  • CAAX prenyl protease,OTTHUMP00000006394,farnesylated-proteins converting enzyme 1,prenyl protein-specific endoprotease 1,zinc metalloproteinase STE24
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