Western blot analysis of USP11 polyclonal antibody (Cat # PAB4191) in Jurkat cell line lysates (35 ug/lane). USP11 (arrow) was detected using the purified USP11 polyclonal antibody (Cat # PAB4191) (1 : 60 dilution).
Formalin-fixed and paraffin-embedded human cancer tissue reacted with USP11 polyclonal antibody (Cat # PAB4191) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . BC = breast carcinoma .
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq