PTP4A3 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of multiple cells cell lysate (35 ug/lane) with PTP4A3 polyclonal antibody (Cat # PAB4120).
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PTP4A3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PTP4A3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of multiple cells cell lysate (35 ug/lane) with PTP4A3 polyclonal antibody (Cat # PAB4120).Enzyme-linked Immunoabsorbent Assay
-
Gene Info — PTP4A3
Entrez GeneID
11156Protein Accession#
NP_116000;O75365Gene Name
PTP4A3
Gene Alias
PRL-3, PRL-R, PRL3
Gene Description
protein tyrosine phosphatase type IVA, member 3
Omim ID
606449Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq
Other Designations
potentially prenylated protein tyrosine phosphatase
-
Interactome
-
Publication Reference
-
Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells.
Wu X, Zeng H, Zhang X, Zhao Y, Sha H, Ge X, Zhang M, Gao X, Xu Q.
The American Journal of Pathology 2004 Jun; 164(6):2039.
-
Structural insights into molecular function of the metastasis-associated phosphatase PRL-3.
Kozlov G, Cheng J, Ziomek E, Banville D, Gehring K, Ekiel I.
The Journal of Biological Chemistry 2004 Mar; 279(12):11882.
-
PRL-3 expression in metastatic cancers.
Bardelli A, Saha S, Sager JA, Romans KE, Xin B, Markowitz SD, Lengauer C, Velculescu VE, Kinzler KW, Vogelstein B.
Clinical Cancer Research 2003 Nov; 9(15):5607.
Application：IF, IHC-P, IP, WB, Human, Human colon cancer cells, Human colorectal tumor.
-
Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com