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Last updated: 2017/4/23

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MVK polyclonal antibody

  • Catalog # : PAB4055
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MVK.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human MVK.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1:100-500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of MVK polyclonal antibody (Cat # PAB4055) in mouse kidney tissue lysate (35 ug/lane). MVK (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4598
  • Gene Name:
  • MVK
  • Gene Alias:
  • FLJ96772,LRBP,MK,MVLK
  • Gene Description:
  • mevalonate kinase
  • Gene Summary:
  • This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • LH receptor mRNA-binding protein,mevalonic aciduria
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