Rabbit polyclonal antibody raised against synthetic peptide of UBE2G1.
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human UBE2G1.
Host:
Rabbit
Reactivity:
Human, Mouse
Form:
Liquid
Purification:
Protein G purification
Recommend Usage:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS (0.09% sodium azide)
Storage Instruction:
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with UBE2G1 polyclonal antibody (Cat # PAB3897) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq
Other Designations:
ubiquitin carrier protein G1,ubiquitin-conjugating enzyme E2G 1,ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans),ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7),ubiquitin-protein ligase G1