GDF10 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
The GDF10 polyclonal antibody (Cat # PAB3881) is used in Western blot to detect GDF10 in A-375 cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with GDF10 polyclonal antibody (Cat # PAB3881) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GDF10.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human GDF10.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The GDF10 polyclonal antibody (Cat # PAB3881) is used in Western blot to detect GDF10 in A-375 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with GDF10 polyclonal antibody (Cat # PAB3881) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. -
Gene Info — GDF10
Entrez GeneID
2662Protein Accession#
NP_004953Gene Name
GDF10
Gene Alias
BMP-3b, BMP3B
Gene Description
growth differentiation factor 10
Omim ID
601361Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000019534|bone morphogenetic protein 3B
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Interactome
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Disease
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Publication Reference
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The family of bone morphogenetic proteins.
Ducy P, Karsenty G.
Kidney International 2000 Jun; 57(6):2207.
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cDNA cloning and genomic structure of human bone morphogenetic protein-3B (BMP-3b).
Hino J, Takao M, Takeshita N, Konno Y, Nishizawa T, Matsuo H, Kangawa K.
Biochemical and Biophysical Research Communications 1996 Jun; 223(2):304.
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Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3.
Cunningham NS, Jenkins NA, Gilbert DJ, Copeland NG, Reddi AH, Lee SJ.
Growth Factors (Chur, Switzerland) 1995 Jan; 12(2):99.
Application：WB-Ce, WB-Tr, Human, Mammalian cells.
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The family of bone morphogenetic proteins.
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