PDPN polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of PDPN polyclonal antibody (Cat # PAB3850) in NCI-H460 cell lysate. PDPN (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PDPN.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PDPN.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PDPN polyclonal antibody (Cat # PAB3850) in NCI-H460 cell lysate. PDPN (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. -
Gene Info — PDPN
Entrez GeneID
10630Protein Accession#
NP_006465Gene Name
PDPN
Gene Alias
AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2
Gene Description
podoplanin
Omim ID
608863Gene Ontology
HyperlinkGene Summary
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000009640|OTTHUMP00000044504|glycoprotein, 36-KD|hT1alpha-1|hT1alpha-2|lung type I cell membrane associated glycoprotein|lung type-I cell membrane-associated glycoprotein|lung type-I cell membrane-associated glycoprotein (T1A-2)
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Interactome
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Disease
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Publication Reference
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Molecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors.
Kato Y, Fujita N, Kunita A, Sato S, Kaneko M, Osawa M, Tsuruo T.
The Journal of Biological Chemistry 2003 Dec; 278(51):51599.
Application：WB-Ce, WB-Tr, IHC-P, Human, Mouse, CA-12, MC3T3-E1, Macrophages, NL-17, CHO cells, Colon.
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Cloning and characterization of gp36, a human mucin-type glycoprotein preferentially expressed in vascular endothelium.
Zimmer G, Oeffner F, Von Messling V, Tschernig T, Groness HJ, Klenk HD, Herrler G.
The Biochemical Journal 1999 Jul; 341(Pt 2):277.
Application：IP, WB-Tr, Dog, MDCK cells.
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Evidence against a role of mouse, rat, and two cloned human t1alpha isoforms as a water channel or a regulator of aquaporin-type water channels.
Ma T, Yang B, Matthay MA, Verkman AS.
American Journal of Respiratory Cell and Molecular Biology 1998 Jul; 19(1):143.
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Molecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors.
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