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Last updated: 2016/12/4
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BMPR1A polyclonal antibody

  • Catalog # : PAB3835
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of BMPR1A.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BMPR1A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Flow Cytometry (1:10-50)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • The BMPR1A polyclonal antibody (Cat # PAB3835) is used in Western blot to detect BMPR1A in mouse muscle tissue lysate (Lane 1) and Hela cell lysate (Lane 2) .
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of WiDr cells using BMPR1A polyclonal antibody (Cat # PAB3835)(bottom histogram) compared to a negative control cell (top histogram).
    FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 657
  • Protein Accession#:
  • NP_004320;P36894
  • Gene Name:
  • BMPR1A
  • Gene Alias:
  • 10q23del,ACVRLK3,ALK3,CD292
  • Gene Description:
  • bone morphogenetic protein receptor, type IA
  • Gene Summary:
  • The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020014,activin A receptor, type II-like kinase 3
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