TFAP2A polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of TFAP2A polyclonal antibody (Cat # PAB3818) in NCI-H460 cell line lysates (35 ug/lane). TFAP2A (arrow) was detected using the purified polyclonal antibody (1:1000 dilution).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TFAP2A.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human TFAP2A.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TFAP2A polyclonal antibody (Cat # PAB3818) in NCI-H460 cell line lysates (35 ug/lane). TFAP2A (arrow) was detected using the purified polyclonal antibody (1:1000 dilution). -
Gene Info — TFAP2A
Entrez GeneID
7020Protein Accession#
NP_003211;P05549Gene Name
TFAP2A
Gene Alias
AP-2, AP-2alpha, AP2TF, BOFS, TFAP2
Gene Description
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Omim ID
107580Gene Ontology
HyperlinkGene Summary
AP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM
Other Designations
OTTHUMP00000016013|OTTHUMP00000016014|activating enhancer-binding protein 2 alpha|transcription factor AP-2 alpha|transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha)
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Interactome
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Disease
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Publication Reference
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PPARalpha and AP-2alpha regulate bombesin receptor subtype 3 expression in ozone-stressed bronchial epithelial cells.
Tan YR, Qin XQ, Xiang Y, Yang T, Qu F, Wang Y, Liu HJ, Weber HC.
The Biochemical Journal 2007 Jul; 405(1):131.
Application：WB-Ce, Human, Human bronchial epithelial cells.
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AP-2 participates in the transcriptional control of the amyloid precursor protein (APP) gene in oral squamous cell carcinoma.
Provenzano MJ, Yu L, Hitchler MJ, Fitzgerald MP, Robinson RA, Wayne S, Ver Meer M, Domann FE.
Experimental and Molecular Pathology 2007 Jun; 83(2):277.
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Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation.
Liu H, Tan BC, Tseng KH, Chuang CP, Yeh CW, Chen KD, Lee SC, Yung BY.
EMBO Reports 2007 Apr; 8(4):394.
Application：ChIP, WB, Human, HL-60 cells.
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PPARalpha and AP-2alpha regulate bombesin receptor subtype 3 expression in ozone-stressed bronchial epithelial cells.
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