TCF7 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TCF7.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human TCF7.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TCF7 polyclonal antibody (Cat # PAB3776) in mouse heart tissue lysate (35 ug/lane). TCF7 (arrow) was detected using the purified polyclonal antibody (1:1000 dilution). -
Gene Info — TCF7
Entrez GeneID
6932Protein Accession#
NP_003193;Q86WR9Gene Name
TCF7
Gene Alias
FLJ36364, MGC47735, TCF-1
Gene Description
transcription factor 7 (T-cell specific, HMG-box)
Omim ID
189908Gene Ontology
HyperlinkGene Summary
O
Other Designations
OTTHUMP00000159391|Transcription factor-7, T-cell specific
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Interactome
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Pathway
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Disease
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Publication Reference
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Wnt activates the Tak1/Nemo-like kinase pathway.
Smit L, Baas A, Kuipers J, Korswagen H, van de Wetering M, Clevers H.
The Journal of Biological Chemistry 2004 Feb; 279(17):17232.
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Initiation and limitation of Ly-49A NK cell receptor acquisition by T cell factor-1.
Ioannidis V, Kunz B, Tanamachi DM, Scarpellino L, Held W.
The Journal of Immunology 2003 Jul; 171(2):769.
Application:WB-Ce, Mouse, NK cells.
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A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes.
Noble JA, White AM, Lazzeroni LC, Valdes AM, Mirel DB, Reynolds R, Grupe A, Aud D, Peltz G, Erlich HA.
Diabetes 2003 Jun; 52(6):1579.
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Wnt activates the Tak1/Nemo-like kinase pathway.
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