Western blot analysis of NMD3 polyclonal antibody (Cat # PAB3770) in mouse heart (left) and T-47D (right) tissue lysates (35 ug/lane). NMD3 (arrow) was detected using the purified polyclonal antibody (1:1000 dilution).
Ribosomes are composed of 60S and 40S subunits that are assembled in the nucleolus and exported to the cytoplasm through nuclear pore complexes in the nuclear envelope. NMD3 is an adaptor for 60S subunit export via the CRM1 (XPO1; MIM 602559) pathway (Trotta et al., 2003 [PubMed 12773398]).[supplied by OMIM