NMD3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NMD3.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human NMD3.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of NMD3 polyclonal antibody (Cat # PAB3770) in mouse heart (left) and T-47D (right) tissue lysates (35 ug/lane). NMD3 (arrow) was detected using the purified polyclonal antibody (1:1000 dilution). -
Gene Info — NMD3
Entrez GeneID
51068Protein Accession#
NP_057022;Q96D46Gene Name
NMD3
Gene Alias
CGI-07, FLJ21053
Gene Description
NMD3 homolog (S. cerevisiae)
Omim ID
611021Gene Ontology
HyperlinkGene Summary
Ribosomes are composed of 60S and 40S subunits that are assembled in the nucleolus and exported to the cytoplasm through nuclear pore complexes in the nuclear envelope. NMD3 is an adaptor for 60S subunit export via the CRM1 (XPO1; MIM 602559) pathway (Trotta et al., 2003 [PubMed 12773398]).[supplied by OMIM
Other Designations
NMD3 homolog
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Interactome
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Publication Reference
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Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates.
Trotta CR, Lund E, Kahan L, Johnson AW, Dahlberg JE.
The EMBO Journal 2003 Jun; 22(11):2841.
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NMD3 encodes an essential cytoplasmic protein required for stable 60S ribosomal subunits in Saccharomyces cerevisiae.
Ho JH, Johnson AW.
Molecular and Cellular Biology 1999 Mar; 19(3):2389.
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Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates.
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