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Last updated: 2016/10/23
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IDH3A polyclonal antibody

  • Catalog # : PAB3735
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of IDH3A.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human IDH3A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of IDH3A polyclonal antibody (Cat # PAB3735) in (1) MCF-7, (2) Jurkat cell line lysates (35ug/lane).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3419
  • Protein Accession#:
  • NP_005521;P50213
  • Gene Name:
  • IDH3A
  • Gene Alias:
  • -
  • Gene Description:
  • isocitrate dehydrogenase 3 (NAD+) alpha
  • Gene Summary:
  • Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq
  • Other Designations:
  • H-IDH alpha,NAD(H)-specific isocitrate dehydrogenase alpha subunit,NAD+-specific ICDH,isocitrate dehydrogenase (NAD+) alpha chain,isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial,isocitric dehydrogenase
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