Product Browser

Last updated: 2016/12/4
  • Related Product Showcase
  • By Research Area

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

UPF1 polyclonal antibody

  • Catalog # : PAB3694
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of UPF1.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human UPF1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of UPF1 (arrow) using UPF1 polyclonal antibody (Cat # PAB3694).
    293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the UPF1 gene (Lane 2).
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5976
  • Protein Accession#:
  • NP_002902;Q92900
  • Gene Name:
  • UPF1
  • Gene Alias:
  • FLJ43809,FLJ46894,HUPF1,KIAA0221,NORF1,RENT1,pNORF1
  • Gene Description:
  • UPF1 regulator of nonsense transcripts homolog (yeast)
  • Gene Summary:
  • This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq
  • Other Designations:
  • UP Frameshift 1,delta helicase,nonsense mRNA reducing factor 1,regulator of nonsense transcripts 1,up-frameshift mutation 1 homolog,yeast Upf1p homolog
  • RSS
  • YouTube
  • Linkedin
  • Facebook