BMP10 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BMP10.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BMP10.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of BMP10 polyclonal antibody (Cat # PAB3667) in 293 cell line lysates (35 ug/lane). BMP10 (arrow) was detected using the purified polyclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with BMP10 polyclonal antibody (Cat # PAB3667) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. -
Gene Info — BMP10
Entrez GeneID
27302Protein Accession#
O95393Gene Name
BMP10
Gene Alias
MGC126783
Gene Description
bone morphogenetic protein 10
Omim ID
608748Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TGF-beta family of growth factors. Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart. In human, this protein may signal through receptor serine/threonine kinases. [provided by RefSeq
Other Designations
OTTHUMP00000159973
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Interactome
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Disease
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Publication Reference
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Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily.
Neuhaus H, Rosen V, Thies RS.
Mechanisms of Development 1999 Feb; 80(2):181.
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Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily.
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