Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with SIGLEC11 polyclonal antibody (Cat # PAB3646) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
SIGLECs are a family of cell surface lectins defined by shared structural motifs in the first 2 immunoglobulin (Ig)-like domains and by their ability to recognize sialic acids via the first Ig V set domain.[supplied by OMIM