SIGLEC10 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate (35 ug/lane) with SIGLEC10 polyclonal antibody (Cat # PAB3644).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SIGLEC10.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SIGLEC10.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate (35 ug/lane) with SIGLEC10 polyclonal antibody (Cat # PAB3644). -
Gene Info — SIGLEC10
Entrez GeneID
89790Protein Accession#
Q96LC7Gene Name
SIGLEC10
Gene Alias
MGC126774, PRO940, SIGLEC-10, SLG2
Gene Description
sialic acid binding Ig-like lectin 10
Omim ID
606091Gene Ontology
HyperlinkGene Summary
SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).[supplied by OMIM
Other Designations
sialic acid binding Ig-like lectin 10 Ig-like lectin 7|siglec-like gene 2
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Interactome
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Publication Reference
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA,
PNAS 2002 Dec; 99(26):16899.
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Cloning of two new splice variants of Siglec-10 and mapping of the interaction between Siglec-10 and SHP-1.
Kitzig F, Martinez-Barriocanal A, Lopez-Botet M, Sayos J.
Biochemical and Biophysical Research Communications 2002 Aug; 296(2):355.
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Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells.
Li N, Zhang W, Wan T, Zhang J, Chen T, Yu Y, Wang J, Cao X.
The Journal of Biological Chemistry 2001 Jul; 276(30):28106.
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
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