C1QBP polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of C1QBP polyclonal antibody (Cat # PAB3524) in HepG2 cell line lysates (35 ug/lane).C1QBP (arrow) was detected using the purified polyclonal antibody (1:1000 dilution).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of C1QBP.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human C1QBP.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of C1QBP polyclonal antibody (Cat # PAB3524) in HepG2 cell line lysates (35 ug/lane).C1QBP (arrow) was detected using the purified polyclonal antibody (1:1000 dilution). -
Gene Info — C1QBP
Entrez GeneID
708Protein Accession#
NP_001203;Q07021Gene Name
C1QBP
Gene Alias
GC1QBP, HABP1, SF2p32, gC1Q-R, gC1qR, p32
Gene Description
complement component 1, q subcomponent binding protein
Omim ID
601269Gene Ontology
HyperlinkGene Summary
The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. [provided by RefSeq
Other Designations
C1q globular domain-binding protein|hyaluronan-binding protein 1|splicing factor SF2-associated protein
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Interactome
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Disease
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Publication Reference
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Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.
Biswas AK, Hafiz A, Banerjee B, Kim KS, Datta K, Chitnis CE.
PLoS Pathogens 2007 Sep; 3(9):1271.
Application：Flow Cyt, Func, WB, Human, Human brain microvascular endothelial cells, HuVECs.
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The exosporium of B. cereus contains a binding site for gC1qR/p33: implication in spore attachment and/or entry.
Ghebrehiwet B, Tantral L, Titmus MA, Panessa-Warren BJ, Tortora GT, Wong SS, Warren JB.
Advances in Experimental Medicine and Biology 2007 Feb; 598:181.
Application：ELISA, Func, B.cereus, B.cereus spores.
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Protruding disordered loop of gC1qR is specifically exposed and related to antiapoptotic property in germ cell lineage.
Kitazawa S, Takenaka A, Kondo T, Mizoguchi A, Kitazawa R.
Histochemistry and Cell Biology 2006 Dec; 126(6):665.
Application：WB-Tr, Human, ITO-II, TCam-2, Colo201 cells.
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Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.
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