Western blot analysis of RIPK2 polyclonal antibody (Cat # PAB3498) in mouse cerebellum tissue lysate. RIPK2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with RIPK2 polyclonal antibody (Cat # PAB3498) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq
CARD-carrying kinase,CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase,growth-inhibiting gene 30,receptor interacting protein 2,receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP