Western blot analysis of ROR1 (arrow) using ROR1 polyclonal antibody (Cat # PAB3383). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ROR1 gene (Lane 2).
Flow cytometric analysis of NCI-H460 cells using ROR1 polyclonal antibody (Cat # PAB3383)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
The protein encoded by this gene is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq