INSRR polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of INSRR.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human INSRR.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with INSRR polyclonal antibody (Cat # PAB3358) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. -
Gene Info — INSRR
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Interactome
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Pathway
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Disease
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Publication Reference
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Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor.
Hanze J, Berthold A, Klammt J, Gallaher B, Siebler T, Kratzsch J, Elmlinger M, Kiess W.
Hormone and Metabolic Research 1999 Feb; 31(2-3):77.
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The assignment of the human insulin receptor-related receptor gene (INSRR) to chromosome 1q21-->q23 by the use of radiation hybrid mapping.
Whitmore TE, Maurer MF, Day HL, Jelmberg AC, Dasovich MM, Sundborg LM, Burkhead SK, Heipel MD, Madden KL, Kramer JM, Kuijper JL, Xu WF, Jaspers SR, Holly RD, Lok S.
Cytogenetics and Cell Genetics 1999 Jan; 87(1-2):93.
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Primary structure of a putative receptor for a ligand of the insulin family.
Shier P, Watt VM.
The Journal of Biological Chemistry 1989 Sep; 264(25):14605.
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Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor.
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