TTK polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TTK.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human TTK.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The TTK polyclonal antibody (Cat # PAB3320) is used in Western blot to detect TTK in Jurkat cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with TTK polyclonal antibody (Cat # PAB3320) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. -
Gene Info — TTK
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Interactome
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Pathway
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Disease
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Publication Reference
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Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas.
Engqvist H, Parris TZ, Kovács A, Nemes S, Werner Rönnerman E, De Lara S, Biermann J, Sundfeldt K, Karlsson P, Helou K.
BMC Cancer 2019 Sep; 19(1):928.
Application:IHC-P, Human, Ovarian tumor.
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Expression of TTK, a novel human protein kinase, is associated with cell proliferation.
Mills GB, Schmandt R, McGill M, Amendola A, Hill M, Jacobs K, May C, Rodricks AM, Campbell S, Hogg D.
The Journal of Biological Chemistry 1992 Aug; 267(22):16000.
Application:IP, Human, Jurkat cells.
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Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas.
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