GNB2L1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GNB2L1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human GNB2L1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
The GNB2L1 polyclonal antibody (Cat # PAB3270) is used in Western blot to detect GNB2L1 in Ramos cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with GNB2L1 polyclonal antibody (Cat # PAB3270) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma. -
Gene Info — CDR2
Entrez GeneID
1039Protein Accession#
NP_006089Gene Name
CDR2
Gene Alias
CDR62, Yo
Gene Description
cerebellar degeneration-related protein 2, 62kDa
Omim ID
117340Gene Ontology
HyperlinkGene Summary
O
Other Designations
Yo paraneoplastic antigen|cerebellar degeneration-related antigen-2 (62kD)|cerebellar degeneration-related protein (62kD)|cerebellar degeneration-related protein 2|major Yo paraneoplastic antigen|paraneoplastic cerebellar degeneration-associated antigen
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Interactome
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Disease
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Publication Reference
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Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly.
Ceci M, Gaviraghi C, Gorrini C, Sala LA, Offenhauser N, Marchisio PC, Biffo S.
Nature 2003 Dec; 426(6966):579.
Application:WB, Human, HeLa cells.
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The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex.
Usacheva A, Tian X, Sandoval R, Salvi D, Levy D, Colamonici OR.
Journal of Immunology 2003 Sep; 171(6):2989.
Application:WB, Human, U-266 cells.
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RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.
Kiely PA, Sant A, O'Connor R.
The Journal of Biological Chemistry 2002 Jun; 277(25):22581.
Application:WB-Tr, Human, Monkey, Mouse, COS, MCF-7 cells, Mouse fibroblasts.
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Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly.
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