Formalin-fixed and paraffin-embedded human cancer tissue reacted with PIP4K2B polyclonal antibody (Cat # PAB3236) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq
1-phosphatidylinositol-4-phosphate kinase,PTDINS(4)P-5-kinase,diphosphoinositide kinase,phosphatidylinositol-4-phosphate 5-kinase, type II, beta