PIK3R5 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PIK3R5.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to internal region of human PIK3R5.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PIK3R5 polyclonal antibody (Cat # PAB3224) in K-562 cell line lysates (35 ug/lane). PIK3R5 (arrow) was detected using the purified polyclonal antibody. -
Gene Info — PIK3R5
Entrez GeneID
23533Protein Accession#
NP_055123;Q8WYR1Gene Name
PIK3R5
Gene Alias
F730038I15Rik, FOAP-2, P101-PI3K, p101
Gene Description
phosphoinositide-3-kinase, regulatory subunit 5
Omim ID
611317Gene Ontology
HyperlinkGene Summary
Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit (Brock et al., 2003 [PubMed 12507995]).[supplied by OMIM
Other Designations
phosphoinositide-3-kinase, regulatory subunit 5, p101|phosphoinositide-3-kinase, regulatory subunit, polypeptide p101
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Interactome
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Pathway
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Disease
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Publication Reference
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Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma.
Brock C, Schaefer M, Reusch HP, Czupalla C, Michalke M, Spicher K, Schultz G, Nurnberg B.
The Journal of Cell Biology 2003 Jan; 160(1):89.
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Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma.
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