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PIK3C2A polyclonal antibody

  • Catalog # : PAB3206
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PIK3C2A.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PIK3C2A.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of PIK3C2A polyclonal antibody (Cat # PAB3206) in 293 cell lysate. PIK3C2A (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5286
  • Gene Name:
  • PIK3C2A
  • Gene Alias:
  • CPK,DKFZp686L193,MGC142218,PI3-K-C2(ALPHA),PI3-K-C2A
  • Gene Description:
  • phosphoinositide-3-kinase, class 2, alpha polypeptide
  • Gene Summary:
  • The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq
  • Other Designations:
  • C2-containing phosphatidylinositol kinase,PI3K-C2alpha
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