MUC5B polyclonal antibody
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More Files
- More Functions
Immunohistochemistry
Immunohistochemical staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry
Immunohistochemical staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry
Immunohistochemical staining of human cervix shows very strong extracellular space positivity in glandular cells.
Immunohistochemistry
Immunohistochemical staining of human lower gastrointestinal shows strong extracellular space positivity in glandular cells.
Immunofluorescence
Immunofluorescent staining of human cell line A549 shows localization to vesicles.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human MUC5B.
Sequence
CTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTPFTFTTAWVPHSTTSPALPVSTVCVREVCRWSSWYNGHRPEPGLGGGDFETFENLRQRGYQVCPVLA
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts to MUC5B.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (0.25-2 ug/mL)
Immunohistochemistry (1:500 - 1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemical staining of human pancreas shows no positivity in exocrine glandular cells as expected.Immunohistochemistry
Immunohistochemical staining of human skeletal muscle shows no positivity in myocytes as expected.Immunohistochemistry
Immunohistochemical staining of human cervix shows very strong extracellular space positivity in glandular cells.Immunohistochemistry
Immunohistochemical staining of human lower gastrointestinal shows strong extracellular space positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line A549 shows localization to vesicles. -
Gene Info — MUC5B
Entrez GeneID
727897Gene Name
MUC5B
Gene Alias
MG1, MUC5, MUC9
Gene Description
mucin 5B, oligomeric mucus/gel-forming
Omim ID
600770Gene Ontology
HyperlinkGene Summary
Mucins are high molecular mass, highly glycosylated macromolecules that are the major components of mucus secretions. MUC5B is a salivary mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva. It is composed of 14.9% protein, 78.1% carbohydrate, and 7% sulfate (Troxler et al., 1995 [PubMed 8554565]).[supplied by OMIM
Other Designations
cervical mucin MUC5B|high molecular weight mucin|mucin 5, subtype B, tracheobronchial|mucin, salivary (high molecular weight)
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Interactome
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Disease
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