SMARCA2 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry
Immunohistochemical staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.
Immunohistochemistry
Immunohistochemical staining of human pancreas shows moderate nuclear positivity in exocrine glandular cells.
Immunohistochemistry
Immunohistochemical staining of human fallopian tube shows strong nuclear positivity in glandular cells.
Immunohistochemistry
Immunohistochemical staining of human testis shows strong nuclear positivity in seminiferous ducts.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm and vesicles.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human SMARCA2.
Sequence
SPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVP
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts to SMARCA2.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (0.25-2 ug/mL)
Immunohistochemistry (1:500 - 1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemical staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.Immunohistochemistry
Immunohistochemical staining of human pancreas shows moderate nuclear positivity in exocrine glandular cells.Immunohistochemistry
Immunohistochemical staining of human fallopian tube shows strong nuclear positivity in glandular cells.Immunohistochemistry
Immunohistochemical staining of human testis shows strong nuclear positivity in seminiferous ducts.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm and vesicles. -
Gene Info — SMARCA2
Entrez GeneID
6595Gene Name
SMARCA2
Gene Alias
BAF190, BRM, FLJ36757, MGC74511, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a
Gene Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Omim ID
600014Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq
Other Designations
OTTHUMP00000020970|OTTHUMP00000020971|SNF2-alpha|SNF2-like 2|SNF2/SWI2-like protein 2|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2|global transcription activator homologous sequence|sucrose nonfermenting 2-like protein 2
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Interactome
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Disease
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