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Last updated: 2022/5/22

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SMARCA2 polyclonal antibody 

  • Catalog # : PAB31822
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against recombinant human SMARCA2.
  • Sequence:
  • SPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVP
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts to SMARCA2.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (0.25-2 ug/mL)
    Immunohistochemistry (1:500 - 1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH7.2 (40% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of human testis shows strong nuclear positivity in seminiferous ducts.
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of human fallopian tube shows strong nuclear positivity in glandular cells.
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of human pancreas shows moderate nuclear positivity in exocrine glandular cells.
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm and vesicles.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 6595
  • Gene Name:
  • SMARCA2
  • Gene Alias:
  • BAF190,BRM,FLJ36757,MGC74511,SNF2,SNF2L2,SNF2LA,SWI2,Sth1p,hBRM,hSNF2a
  • Gene Description:
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
  • Gene Summary:
  • The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020970,OTTHUMP00000020971,SNF2-alpha,SNF2-like 2,SNF2/SWI2-like protein 2,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2,global transcription activator homologous sequence,sucrose nonfermenting 2-like protein 2
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