ATRIP (phospho S68) polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of 3T3 cell lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human ATRIP (phospho S68).
Immunogen
A synthetic peptide corresponding to amino acids 10-90 of human ATRIP (phospho S68).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of ATRIP protein only when phosphorylated at S68.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
ELISA (1:40000)
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 0.5% BSA and 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of 3T3 cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ATRIP
Entrez GeneID
84126Protein Accession#
Q8WXE1Gene Name
ATRIP
Gene Alias
DKFZp762J2115, FLJ12343, MGC20625, MGC21482, MGC26740
Gene Description
ATR interacting protein
Omim ID
606605Gene Ontology
HyperlinkGene Summary
The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Disease
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