ADAM17 (phospho T735) polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of human ADAM17 (phospho T735).
Immunogen
A synthetic peptide corresponding to amino acids 670-750 of human ADAM17 (phospho T735).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of ADAM17 protein only when phosphorylated at T735.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
ELISA (1:20000)
Immunohistochemistry (1:100-300)
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 0.5% BSA and 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — ADAM17
Entrez GeneID
6868Protein Accession#
P78536Gene Name
ADAM17
Gene Alias
CD156b, MGC71942, TACE, cSVP
Gene Description
ADAM metallopeptidase domain 17
Omim ID
603639Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq
Other Designations
TNF-alpha converting enzyme|a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme)|snake venom-like protease|tumor necrosis factor, alpha, converting enzyme
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com