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CCL2 polyclonal antibody

  • Catalog # : PAB31623
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant human CCL2.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 25-99 of human CCL2.
  • Sequence:
  • PDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunofluorescence (1-4 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C for short term storage. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin shows moderate positivity in plasma.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of human cell line BJ shows localization to the Golgi apparatus. Antibody staining is shown in green.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6347
  • Gene Name:
  • CCL2
  • Gene Alias:
  • GDCF-2,HC11,HSMCR30,MCAF,MCP-1,MCP1,MGC9434,SCYA2,SMC-CF
  • Gene Description:
  • chemokine (C-C motif) ligand 2
  • Gene Summary:
  • This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq
  • Other Designations:
  • monocyte chemoattractant protein-1,monocyte chemotactic and activating factor,monocyte chemotactic protein 1, homologous to mouse Sig-je,monocyte secretory protein JE,small inducible cytokine A2,small inducible cytokine A2 (monocyte chemotactic protein 1,
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